Precision Medicine for a Changing Population: 

Workshop on the Italian Context

 Precision Medicine, New Italians and Health Disparities in Italy

18 September 2018

European Institute of Oncology, IFOM-IEO Campus Conference Room

Via Adamello 16, 20139 Milano

Organizing committee: STS Unit European Institute of Oncology

Giuseppe Testa, MD, PhD, MA, Full Professor of Molecular Biology, University of Milan; Director of the Laboratory of Stem Cell Epigenetics, European Institute of Oncology

Nadav Even Chorev, PhD, Post-Doctoral Fellow in the STS Unit of the Stem Cell Epigenetics Lab, European Institute of Oncology

 Ilaria Galasso, PhD Student in Foundation of Life Sciences, Bioethics and Cognitive Sciences at European School of Molecular Medicine, University of Milan and European Institute of Oncology

 Luca Marelli, PhD, Marie Skłodowska-Curie Fellow, Life Sciences & Society Lab, KU Leuven; Post-Doctoral Fellow in the STS Unit of the Stem Cell Epigenetics Lab, European Institute of Oncology

Acknowledgments:

This workshop is organized by the Science and Technology Studies (STS) Research Unit at the European Institute of Oncology (IEO). The workshop received funding from the European Association for the Study of Science and Technology (EASST) 2018 Fund, is supported by the Italian Association for Social Studies of Science and Technology (STS Italia). It is hosted by the European Institute of Oncology (IEO) with the help of the event coordination from the SEMM Foundation (European School of Molecular Medicine).

Workshop Description:

The workshop aims at a multidisciplinary analysis of the latest medical developments in conjunction with the most salient current societal transformations and needs. To this end it is organized as a strategic dialogue to harness the societal opportunities and challenges in the implementation of precision medicine in light of the ongoing societal and demographic transformations of the Italian population.

In recent years, migration has rendered the Italian population increasingly multi-ethnic and diverse, yet also afflicted with forms of discrimination and geographical segregation which further exacerbate health inequalities. Precision medicine mines individual traits for personalized treatments. Placing this emerging medical practice within the context of a changing population creates multiple tensions, which this workshop aims at disentangling.

The workshop focuses on strategies to build inclusive representation of varied groups and identities into efforts to advance precision medicine in Italy. Specifically, it aims to chart how inclusive representation could improve both the scientific significance of precision medicine and the societal fairness in distributing its expected medical benefits – thus bringing to the fore the contribution that medical research can bring to societal integration and vice-versa.

The workshop is organized as a public, facilitated roundtable discussion, engaging different stakeholders in an interdisciplinary dialogue on alleviating Italian health inequalities through precision medicine.

The number of participants will be limited to 190. Due to seating limitations, we will confirm your registration on first-come-first-served basis after the registration deadline.

Registration is free of charge and covers only attendance to the scientific sessions

Please Register HERE.

Program

10.30

Welcome (STS Unit European Institute of Oncology)

 Introduction

  • Ilaria Galasso (PhD Student in Foundation of Life Sciences, Bioethics and Cognitive Sciences at European School of Molecular Medicine, University of Milan and European Institute of Oncology)

Precision Medicine and Health Disparities: Opportunities and Concerns

 11.00

  • PANEL 1: Migrants and New Italians: Discrimination and Health

Panel description: The current socio-political context makes immigrants and new Italians especially vulnerable in terms of health. Their disadvantageous initial conditions as immigrants and the social tensions challenging their assimilation in the labor market and in higher education, often condemn these populations to poverty, low education levels, and segregation– thus exacerbating the effects of social and environmental determinants of health. Against this background, this session will focus on making sense of and critically examining evolving health disparities, and how the latter are brought to bear to the alignment of medical research and practice with the new shape of Italian society.

Moderator: Luca Marelli, PhD (Marie Skłodowska-Curie Fellow, Life Sciences & Society Lab, KU Leuven; Post-Doctoral Fellow in the STS Unit of the Stem Cell Epigenetics Lab, European Institute of Oncology)

Panelists:

  • Martino Ardigò, MD, PhD (Researcher, Centre for International Health; University of Bologna):

“Bios VS Zoe: is the focus on biomedicine a significant risk for health inequalities?”

  • Valeria Ottonelli, PhD (Associate Professor of Political Philosophy, University of Genova):
  • “The difference that migration makes. Health inequalities and the distinctiveness of migration”

  • Emilio Di Maria, MD, PhD (Assistant Professor of Medical Genetics, University of Genova; Consultant Clinical Geneticist, Galliera Hospital; Coordinator Gruppo Ligure Immigrazione e Salute, Società Italiana Medicina delle Migrazioni):

“Health right and healthcare for migrant persons: from evidence to equity”

  • Ilaria Galasso (PhD Student in Foundation of Life Sciences, Bioethics and Cognitive Sciences at European School of Molecular Medicine, University of Milan and European Institute of Oncology):

“The “Societal Potential” of Precision Medicine as a Solution to Exclusivity and Discrimination: International Case Studies”

 

 13.30: End of the morning panel and free time

14.30

  • PANEL 2: Italian Precision Medicine and Health Equity

Panel description: Precision medicine focuses on individual variability to deliver targeted prevention strategies and treatments. This approach builds on correlations between personal traits and contexts, and wider health, lifestyle and disease conditions and predispositions. This session will focus on possible strategies to frame precision medicine in the context of the changing Italian society, by considering the impact of its inclusive implementation. This discussion will facilitate to better understand the specific health needs and vulnerabilities of migrants and new Italians, and to improve the equity of healthcare outcomes across the Italian population.

Moderator: Ilaria Galasso (PhD Student in Foundation of Life Sciences, Bioethics and Cognitive Sciences at European School of Molecular Medicine, University of Milan and European Institute of Oncology)

 Panelists:

 

  • Pier Giuseppe Pelicci, MD, PhD (Director of Research and Chairman of the Department of Experimental Oncology, IEO, Milan; Full Professor of Pathology, University of Milan):
  • “Alliance Against Cancer (ACC): A draft of a National Program of personalized medicine”

  • Giuseppe Remuzzi, MD, FRCP (Director of Istituto Ricerche Farmacologiche Mario Negri; Professor of Nephrology and Director of the Department of Immunology and Clinical Transplantation, Ospedali Riuniti di Bergamo; Director of the Division of Nephrology and Dialysis, Ospedali Riuniti di Bergamo; Full Professor of Nephrology, University of Milan; Member of Board of Directors of Istituto Superiore di Sanità):
  • “Will Precision Medicine fail just as its predecessors did?”

  • Stefano Crabu, PhD (Assistant Professor, Department of Design, Polytechnic University of Milan):

“Politics of personalization: empowering “potential patients” and healthcare practitioners in the precision medicine era”

  • Nadav Even Chorev, PhD (Post-doctoral Fellow in the STS Unit of the Stem Cell Epigenetics Lab, European Institute of Oncology):

“Continuities and Decontextualization in Personalized Cancer Medicine”

  • Giuseppe Testa, MD, PhD, MA (Full Professor of Molecular Biology, University of Milan; Director of the Laboratory of Stem Cell Epigenetics, European Institute of Oncology)

“The mirage of a space between precision medicine and precision public health?”

17.00

  • Conclusions
  • Luca Marelli, PhD (Marie Skłodowska-Curie Fellow, Life Sciences & Society Lab, KU Leuven; Post-Doctoral Fellow in the STS Unit of the Stem Cell Epigenetics Lab, European Institute of Oncology):

Concluding Remarks: Lessons Learned and Emerging Future Directions

 17.30     Adjourn

For more information, contact nadav.evenchorev@ieo.it ; ilaria.galasso@ieo.it

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